Palavra-chave: TWO-LAYER APPROACH

ADVANCED CONTROLLER HYDROGENATION DYNAMIC MODELING SIMULATION OPTIMIZATION THREE-PHASE CATALYTIC REACTOR. DYNAMIC MODELLING HYDROGENATION, HYDROGENATION CATALYTIC REACTOR REAL TIME INTEGRATION DYNAMICS MODELING INTEGRATION OF CONTROL AND OPTIMIZATION ALGORITHMS AND SIMULATION CONTROLLER ADVANCED GENETIC ALGORITHMS ACRYLIC ACID MODEL-BASED CONTROL BIOTECHNOLOGICAL PROCESS OPTIMAL OPERATIONAL CONTROL BIOPROCESS FERMENTATION