Exact and Earth Sciences

Biomaterials; Biomimetic materials; Surface modification
Academic Profiles

Latest training
2021 - 2024     Doctorate, Universidade Federal do Piauí
Research Activities

Mucociliary clearance is the main defense mechanism of the airways. The cilia-like structure arranged in the epithelial cells on a micrometric scale, similar to hair strands, moves the accumulated mucus unidirectionally, promoting airway cleansing. Mucin glycopolymers are deposited in the periciliary layer and form a dense network capable of promoting metachronal movement. Bioinspired by this type of natural arrangement, the proposal aims to produce artificial magnetic microcilia with supramolecular glycopolymers based on the mucin structure activated by a magnetic field to move, pushing the mucus unidirectionally and cleaning the patient's airways. The correct functioning of the device will allow an improvement of commercially available devices that consist of a silicone surface incapable of promoting the movement of accumulated mucus. The structure and function of the devices will be improved in order to reduce the formation of biofilm caused by microorganisms present in the air breathed. With the results, we intend to create a product that can bring a better quality of life to a portion of the population that depends on the prolonged use of these commercial stents that can last months or years.

Keywords
Biomimetic materials, Biopolymers, Polymers, Hydrogels, Bioinspired materials, Click Chemistry, 3D Bioprinting, Tissue Engineering, Biomaterials
Keywords (lattes)
Co-authors
Abstract Lattes
Cientista e Empreendedor. Possui graduação em Química (IFPI, 2016). Mestrado (UFPI, 2020) e Doutorado (UFPI, 2024) em Ciência e Engenharia dos Materiais (Biomateriais). Atualmente é Pesquisador Pós-Doc no Instituo de Química da UNICAMP. Foi pesquisador visitante no Departamento de Engenharia em Medicina do Brigham and Women's Hospital, Harvard Medical School. É sócio fundador da THE Bioinks, startup especializada na produção de biomateriais de composição e propriedades customizáveis. Possui experiência científica na interface Materiais - Química - Engenharia de Tecidos. Atua diretamente na produção de Biomateriais Biomiméticos e Bioinspirados aplicados a Engenharia de Tecidos e Medicina Regenerativa.
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English Comprehends Well , Speaks Well , Reads Well , Writes Well
Portuguese Comprehends Well , Speaks Well , Reads Well , Writes Well
Spanish Comprehends Well , Speaks Reasonably , Reads Well , Writes Reasonably
French Comprehends Reasonably , Speaks Little , Reads Reasonably , Writes Little
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