Our research group has carried out research in human beings, and we have investigated the effects of obesity, sedentary lifestyle, aging and comorbidities, especially on body composition, metabolic profile and immune system, as well as adaptations to physical exercise as a non-pharmacological treatment and its effects. respective mechanisms. For this, we incorporate in our researches/publications, new methodologies for the collection of biological material, such as biopsy of muscle tissue and adipose tissue, as well as methodologies related to Omic Sciences (genomics, transcriptomics and metabolomics) that are at the frontier of knowledge in the area, and which made it possible to improve the impact factor of publications and increase the visibility of the group.